Website outages and system releases

The European Medicines Agency (EMA) makes upgrades to this website and the Clinical Trials Information System (CTIS) from time to time, to improve user experience.

During these times, CTIS and this website may be temporarily unavailable or not work optimally.

You can see when we are planning the next outage below. Registered users can also see notice of any planned interruptions in EMA Service Desk.

Below you can find the full release notes and a list of any outstanding issues and proposed workarounds for these issues.

Some functionalities within CTIS rely on other systems which are also maintained by EMA. Upgrades and related work on any of these systems can affect CTIS users’ ability to perform some actions. You can see when we are planning the next maintenance on these systems below.

On this page

Planned system interruptions

EMA plans regular maintenance windows for CTIS, during which users are advised to avoid using CTIS or the website:

Monday to Friday, from 18:00 – 21:00 Amsterdam time
Each first Saturday of the month, from 10:00 - 14:00 Amsterdam time

Possible disruptions in OMS on 3 December 2022

On Saturday 3 December 2022, possible restarts and short windows of downtime of OMS are foreseen between 09:00-19:00 CEST. This may impact CTIS users when searching and selecting organisations. We apologise in advance for any inconvenience.

About release notes

These documents outline the latest updates to the CTIS system, including the secure Sponsor and Authority workspaces, and to the Clinical Trials website. Updates may include improvements to existing features and functionality, the addition of new features and functionality and technical improvements.

Release notes December 2022

Release notes v1.0.10.0 (PDF, in English)

Release notes November 2022

Release notes v1.0.9.0 (PDF, in English)

Release notes v1.0.8.0 (PDF, in English)